Worldwide phylogenetic relationship of avian poxviruses

Miklós Gyuranecz, Jeffrey T Foster, Ádám Dán, Hon S. Ip, Kristina F. Egstad, Patricia G. Parker, Jenni M. Higashiguchi, Michael A. Skinner, Ursula Höfle, Zsuzsa Kreizinger, Gerry M. Dorrestein, Szabolcs Solt, Endre Sós, Young Jun Kim, Marcela Uhart, Ariel Pereda, Gisela González-Hein, Hector Hidalgo, Juan Manuel Blanco, Károly Erdélyi

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Poxvirus infections have been found in 230 species of wild and domestic birds worldwide in both terrestrial and marine environments. This ubiquity raises the question of how infection has been transmitted and globally dispersed. We present a comprehensive global phylogeny of 111 novel poxvirus isolates in addition to all available sequences from GenBank. Phylogenetic analysis of the Avipoxvirus genus has traditionally relied on one gene region (4b core protein). In this study we expanded the analyses to include a second locus (DNA polymerase gene), allowing for a more robust phylogenetic framework, finer genetic resolution within specific groups, and the detection of potential recombination. Our phylogenetic results reveal several major features of avipoxvirus evolution and ecology and propose an updated avipoxvirus taxonomy, including three novel subclades. The characterization of poxviruses from 57 species of birds in this study extends the current knowledge of their host range and provides the first evidence of the phylogenetic effect of genetic recombination of avipoxviruses. The repeated occurrence of avian family or order-specific grouping within certain clades (e.g., starling poxvirus, falcon poxvirus, raptor poxvirus, etc.) indicates a marked role of host adaptation, while the sharing of poxvirus species within prey-predator systems emphasizes the capacity for crossspecies infection and limited host adaptation. Our study provides a broad and comprehensive phylogenetic analysis of the Avipoxvirus genus, an ecologically and environmentally important viral group, to formulate a genome sequencing strategy that will clarify avipoxvirus taxonomy.

Original languageEnglish (US)
Pages (from-to)4938-4951
Number of pages14
JournalJournal of Virology
Volume87
Issue number9
DOIs
StatePublished - May 2013

Fingerprint

Avipoxvirus
Poxviridae
phylogeny
Genetic Recombination
Birds
Poxviridae Infections
Raptors
Starlings
infection
taxonomy
Host Specificity
Nucleic Acid Databases
genetic recombination
DNA-Directed DNA Polymerase
Phylogeny
falcons
Infection
Sturnidae
Ecology
birds

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Gyuranecz, M., Foster, J. T., Dán, Á., Ip, H. S., Egstad, K. F., Parker, P. G., ... Erdélyi, K. (2013). Worldwide phylogenetic relationship of avian poxviruses. Journal of Virology, 87(9), 4938-4951. https://doi.org/10.1128/JVI.03183-12

Worldwide phylogenetic relationship of avian poxviruses. / Gyuranecz, Miklós; Foster, Jeffrey T; Dán, Ádám; Ip, Hon S.; Egstad, Kristina F.; Parker, Patricia G.; Higashiguchi, Jenni M.; Skinner, Michael A.; Höfle, Ursula; Kreizinger, Zsuzsa; Dorrestein, Gerry M.; Solt, Szabolcs; Sós, Endre; Kim, Young Jun; Uhart, Marcela; Pereda, Ariel; González-Hein, Gisela; Hidalgo, Hector; Blanco, Juan Manuel; Erdélyi, Károly.

In: Journal of Virology, Vol. 87, No. 9, 05.2013, p. 4938-4951.

Research output: Contribution to journalArticle

Gyuranecz, M, Foster, JT, Dán, Á, Ip, HS, Egstad, KF, Parker, PG, Higashiguchi, JM, Skinner, MA, Höfle, U, Kreizinger, Z, Dorrestein, GM, Solt, S, Sós, E, Kim, YJ, Uhart, M, Pereda, A, González-Hein, G, Hidalgo, H, Blanco, JM & Erdélyi, K 2013, 'Worldwide phylogenetic relationship of avian poxviruses', Journal of Virology, vol. 87, no. 9, pp. 4938-4951. https://doi.org/10.1128/JVI.03183-12
Gyuranecz M, Foster JT, Dán Á, Ip HS, Egstad KF, Parker PG et al. Worldwide phylogenetic relationship of avian poxviruses. Journal of Virology. 2013 May;87(9):4938-4951. https://doi.org/10.1128/JVI.03183-12
Gyuranecz, Miklós ; Foster, Jeffrey T ; Dán, Ádám ; Ip, Hon S. ; Egstad, Kristina F. ; Parker, Patricia G. ; Higashiguchi, Jenni M. ; Skinner, Michael A. ; Höfle, Ursula ; Kreizinger, Zsuzsa ; Dorrestein, Gerry M. ; Solt, Szabolcs ; Sós, Endre ; Kim, Young Jun ; Uhart, Marcela ; Pereda, Ariel ; González-Hein, Gisela ; Hidalgo, Hector ; Blanco, Juan Manuel ; Erdélyi, Károly. / Worldwide phylogenetic relationship of avian poxviruses. In: Journal of Virology. 2013 ; Vol. 87, No. 9. pp. 4938-4951.
@article{99ee92fe20d649b9a79dd833dc39f172,
title = "Worldwide phylogenetic relationship of avian poxviruses",
abstract = "Poxvirus infections have been found in 230 species of wild and domestic birds worldwide in both terrestrial and marine environments. This ubiquity raises the question of how infection has been transmitted and globally dispersed. We present a comprehensive global phylogeny of 111 novel poxvirus isolates in addition to all available sequences from GenBank. Phylogenetic analysis of the Avipoxvirus genus has traditionally relied on one gene region (4b core protein). In this study we expanded the analyses to include a second locus (DNA polymerase gene), allowing for a more robust phylogenetic framework, finer genetic resolution within specific groups, and the detection of potential recombination. Our phylogenetic results reveal several major features of avipoxvirus evolution and ecology and propose an updated avipoxvirus taxonomy, including three novel subclades. The characterization of poxviruses from 57 species of birds in this study extends the current knowledge of their host range and provides the first evidence of the phylogenetic effect of genetic recombination of avipoxviruses. The repeated occurrence of avian family or order-specific grouping within certain clades (e.g., starling poxvirus, falcon poxvirus, raptor poxvirus, etc.) indicates a marked role of host adaptation, while the sharing of poxvirus species within prey-predator systems emphasizes the capacity for crossspecies infection and limited host adaptation. Our study provides a broad and comprehensive phylogenetic analysis of the Avipoxvirus genus, an ecologically and environmentally important viral group, to formulate a genome sequencing strategy that will clarify avipoxvirus taxonomy.",
author = "Mikl{\'o}s Gyuranecz and Foster, {Jeffrey T} and {\'A}d{\'a}m D{\'a}n and Ip, {Hon S.} and Egstad, {Kristina F.} and Parker, {Patricia G.} and Higashiguchi, {Jenni M.} and Skinner, {Michael A.} and Ursula H{\"o}fle and Zsuzsa Kreizinger and Dorrestein, {Gerry M.} and Szabolcs Solt and Endre S{\'o}s and Kim, {Young Jun} and Marcela Uhart and Ariel Pereda and Gisela Gonz{\'a}lez-Hein and Hector Hidalgo and Blanco, {Juan Manuel} and K{\'a}roly Erd{\'e}lyi",
year = "2013",
month = "5",
doi = "10.1128/JVI.03183-12",
language = "English (US)",
volume = "87",
pages = "4938--4951",
journal = "Journal of Virology",
issn = "0022-538X",
publisher = "American Society for Microbiology",
number = "9",

}

TY - JOUR

T1 - Worldwide phylogenetic relationship of avian poxviruses

AU - Gyuranecz, Miklós

AU - Foster, Jeffrey T

AU - Dán, Ádám

AU - Ip, Hon S.

AU - Egstad, Kristina F.

AU - Parker, Patricia G.

AU - Higashiguchi, Jenni M.

AU - Skinner, Michael A.

AU - Höfle, Ursula

AU - Kreizinger, Zsuzsa

AU - Dorrestein, Gerry M.

AU - Solt, Szabolcs

AU - Sós, Endre

AU - Kim, Young Jun

AU - Uhart, Marcela

AU - Pereda, Ariel

AU - González-Hein, Gisela

AU - Hidalgo, Hector

AU - Blanco, Juan Manuel

AU - Erdélyi, Károly

PY - 2013/5

Y1 - 2013/5

N2 - Poxvirus infections have been found in 230 species of wild and domestic birds worldwide in both terrestrial and marine environments. This ubiquity raises the question of how infection has been transmitted and globally dispersed. We present a comprehensive global phylogeny of 111 novel poxvirus isolates in addition to all available sequences from GenBank. Phylogenetic analysis of the Avipoxvirus genus has traditionally relied on one gene region (4b core protein). In this study we expanded the analyses to include a second locus (DNA polymerase gene), allowing for a more robust phylogenetic framework, finer genetic resolution within specific groups, and the detection of potential recombination. Our phylogenetic results reveal several major features of avipoxvirus evolution and ecology and propose an updated avipoxvirus taxonomy, including three novel subclades. The characterization of poxviruses from 57 species of birds in this study extends the current knowledge of their host range and provides the first evidence of the phylogenetic effect of genetic recombination of avipoxviruses. The repeated occurrence of avian family or order-specific grouping within certain clades (e.g., starling poxvirus, falcon poxvirus, raptor poxvirus, etc.) indicates a marked role of host adaptation, while the sharing of poxvirus species within prey-predator systems emphasizes the capacity for crossspecies infection and limited host adaptation. Our study provides a broad and comprehensive phylogenetic analysis of the Avipoxvirus genus, an ecologically and environmentally important viral group, to formulate a genome sequencing strategy that will clarify avipoxvirus taxonomy.

AB - Poxvirus infections have been found in 230 species of wild and domestic birds worldwide in both terrestrial and marine environments. This ubiquity raises the question of how infection has been transmitted and globally dispersed. We present a comprehensive global phylogeny of 111 novel poxvirus isolates in addition to all available sequences from GenBank. Phylogenetic analysis of the Avipoxvirus genus has traditionally relied on one gene region (4b core protein). In this study we expanded the analyses to include a second locus (DNA polymerase gene), allowing for a more robust phylogenetic framework, finer genetic resolution within specific groups, and the detection of potential recombination. Our phylogenetic results reveal several major features of avipoxvirus evolution and ecology and propose an updated avipoxvirus taxonomy, including three novel subclades. The characterization of poxviruses from 57 species of birds in this study extends the current knowledge of their host range and provides the first evidence of the phylogenetic effect of genetic recombination of avipoxviruses. The repeated occurrence of avian family or order-specific grouping within certain clades (e.g., starling poxvirus, falcon poxvirus, raptor poxvirus, etc.) indicates a marked role of host adaptation, while the sharing of poxvirus species within prey-predator systems emphasizes the capacity for crossspecies infection and limited host adaptation. Our study provides a broad and comprehensive phylogenetic analysis of the Avipoxvirus genus, an ecologically and environmentally important viral group, to formulate a genome sequencing strategy that will clarify avipoxvirus taxonomy.

UR - http://www.scopus.com/inward/record.url?scp=84876324467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876324467&partnerID=8YFLogxK

U2 - 10.1128/JVI.03183-12

DO - 10.1128/JVI.03183-12

M3 - Article

VL - 87

SP - 4938

EP - 4951

JO - Journal of Virology

JF - Journal of Virology

SN - 0022-538X

IS - 9

ER -