Valley fever: Finding new places for an old disease: Coccidioides immitis found in Washington state soil associated with recent human infection

Anastasia P. Litvintseva, Nicola Marsden-Haug, Steven Hurst, Heather Hill, Lalitha Gade, Elizabeth M. Driebe, Cindy Ralston, Chandler Roe, Bridget M. Barker, Marcia Goldoft, Paul S Keim, Ron Wohrle, George R. Thompson, David M. Engelthaler, Mary E. Brandt, Tom Chiller

Research output: Contribution to journalArticle

75 Scopus citations

Abstract

We used real-time polymerase chain reaction and culture to demonstrate persistent colonization of soils by Coccidioides immitis, an agent of valley fever, in Washington State linked to recent human infections and located outside the endemic range. Whole-genome sequencing confirmed genetic identity between isolates from soil and one of the case-patients.

Original languageEnglish (US)
Pages (from-to)e1-e3
JournalClinical Infectious Diseases
Volume60
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Keywords

  • Coccidioides
  • Soil detection
  • Valley fever
  • WGS typing

ASJC Scopus subject areas

  • Medicine(all)
  • Microbiology (medical)
  • Infectious Diseases

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  • Cite this

    Litvintseva, A. P., Marsden-Haug, N., Hurst, S., Hill, H., Gade, L., Driebe, E. M., Ralston, C., Roe, C., Barker, B. M., Goldoft, M., Keim, P. S., Wohrle, R., Thompson, G. R., Engelthaler, D. M., Brandt, M. E., & Chiller, T. (2015). Valley fever: Finding new places for an old disease: Coccidioides immitis found in Washington state soil associated with recent human infection. Clinical Infectious Diseases, 60(1), e1-e3. https://doi.org/10.1093/cid/ciu681