Use of dermagraft as an epicardial patch to induce new blood vessels in ischemic cardiac tissue

Anthony Ratcliffe, Lee Landeen, Gail Naughton, Robert S Kellar, Stuart Williams

Research output: Contribution to journalArticle

Abstract

The objective was to determine if DG, when used as an epicardial patch, would stimulate new vessel development within ischemic cardiac tissue. Branch occlusion of the LAD coronary was performed using thermal ligation in SCID mice (n=6 per group) and suture ligation in farm pigs (n=3 per group). DG was sutured onto the epicardium at the ischemic region, whereas untreated control animals received no implant during surgery.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - 2000
Externally publishedYes

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  • Biomedical Engineering

Cite this

Use of dermagraft as an epicardial patch to induce new blood vessels in ischemic cardiac tissue. / Ratcliffe, Anthony; Landeen, Lee; Naughton, Gail; Kellar, Robert S; Williams, Stuart.

In: Annals of Biomedical Engineering, Vol. 28, No. SUPPL. 1, 2000.

Research output: Contribution to journalArticle

Ratcliffe, Anthony ; Landeen, Lee ; Naughton, Gail ; Kellar, Robert S ; Williams, Stuart. / Use of dermagraft as an epicardial patch to induce new blood vessels in ischemic cardiac tissue. In: Annals of Biomedical Engineering. 2000 ; Vol. 28, No. SUPPL. 1.
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