Use of dermagraft as an epicardial patch to induce new blood vessels in ischemic cardiac tissue

Anthony Ratcliffe, Lee Landeen, Gail Naughton, Robert Kellar, Stuart Williams

Research output: Contribution to journalConference article


The objective was to determine if DG, when used as an epicardial patch, would stimulate new vessel development within ischemic cardiac tissue. Branch occlusion of the LAD coronary was performed using thermal ligation in SCID mice (n=6 per group) and suture ligation in farm pigs (n=3 per group). DG was sutured onto the epicardium at the ischemic region, whereas untreated control animals received no implant during surgery.

Original languageEnglish (US)
Pages (from-to)S-119
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000


ASJC Scopus subject areas

  • Biomedical Engineering

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