Ricin forensics: Comparisons to microbial forensics

Jeffrey T. Foster, Robert L. Bull, Paul Keim

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Ricin from the castor bean plant (Ricinus communis) is the most commonly used biological terror agent in the world. The plants are common and the seeds are easy to procure. The protein toxin is extremely potent, relatively simple to extract and disseminate and there is no known antidote. Forensic investigations are similar to those used in microbial toxins where the toxin must be identified and its activity verified, and DNA from the toxin source must be present to be genotyped. Ricin however provides unique genetic challenges because the toxin sample typically provides only trace amounts of mixed DNA from a large number of plants. Furthermore, plants from around the world appear to have only a limited number of sources and are highly similar to one another genetically. Forensics must therefore rely on relatively large numbers of genetic markers to connect samples from a criminal act to those from the purported source.

Original languageEnglish (US)
Title of host publicationMicrobial Forensics
PublisherElsevier
Pages241-250
Number of pages10
ISBN (Electronic)9780128153796
DOIs
StatePublished - Jan 1 2019

Keywords

  • Castor bean
  • Detection
  • Forensics
  • Ricin toxin
  • Ricinus communis
  • Source attribution

ASJC Scopus subject areas

  • Social Sciences(all)

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