Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts

Clifford J. Unkefer, Richard T. Sayre, Jon K. Magnuson, Daniel B. Anderson, Ivan Baxter, Ian K. Blaby, Judith K. Brown, Michael Carleton, Rose Ann Cattolico, Taraka Dale, Timothy P. Devarenne, C. Meghan Downes, Susan K. Dutcher, David T. Fox, Ursula Goodenough, Jan Jaworski, Jonathan E. Holladay, David M. Kramer, Andrew T Koppisch, Mary S. Lipton & 17 others Babetta L. Marrone, Margaret McCormick, István Molnár, John B. Mott, Kimberly L. Ogden, Ellen A. Panisko, Matteo Pellegrini, Juergen Polle, James W. Richardson, Martin Sabarsky, Shawn R. Starkenburg, Gary D. Stormo, Munehiro Teshima, Scott N. Twary, Pat J. Unkefer, Joshua S. Yuan, José A. Olivares

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

In 2010, when the National Alliance for Advanced Biofuels and Bioproducts (NAABB) consortium began, little was known about the molecular basis of algal biomass or oil production. Very few algal genome sequences were available and efforts to identify the best-producing wild species through bioprospecting approaches had largely stalled after the U.S. Department of Energy's Aquatic Species Program. This lack of knowledge included how reduced carbon was partitioned into storage products like triglycerides or starch and the role played by metabolite remodeling in the accumulation of energy-dense storage products. Furthermore, genetic transformation and metabolic engineering approaches to improve algal biomass and oil yields were in their infancy. Genome sequencing and transcriptional profiling were becoming less expensive, however; and the tools to annotate gene expression profiles under various growth and engineered conditions were just starting to be developed for algae. It was in this context that an integrated algal biology program was introduced in the NAABB to address the greatest constraints limiting algal biomass yield. This review describes the NAABB algal biology program, including hypotheses, research objectives, and strategies to move algal biology research into the twenty-first century and to realize the greatest potential of algae biomass systems to produce biofuels.

Original languageEnglish (US)
Pages (from-to)187-215
Number of pages29
JournalAlgal Research
Volume22
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

Fingerprint

biobased products
biofuels
algae
Biological Sciences
biomass
oils
metabolic engineering
genome
energy
infancy
genetic transformation
triacylglycerols
starch
metabolites
gene expression
carbon

Keywords

  • Algal biology
  • Genomics
  • Lipid biosynthesis
  • NAABB
  • National Alliance for advanced biofuels and Bioproducts
  • Proteomics

ASJC Scopus subject areas

  • Agronomy and Crop Science

Cite this

Unkefer, C. J., Sayre, R. T., Magnuson, J. K., Anderson, D. B., Baxter, I., Blaby, I. K., ... Olivares, J. A. (2017). Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts. Algal Research, 22, 187-215. https://doi.org/10.1016/j.algal.2016.06.002

Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts. / Unkefer, Clifford J.; Sayre, Richard T.; Magnuson, Jon K.; Anderson, Daniel B.; Baxter, Ivan; Blaby, Ian K.; Brown, Judith K.; Carleton, Michael; Cattolico, Rose Ann; Dale, Taraka; Devarenne, Timothy P.; Downes, C. Meghan; Dutcher, Susan K.; Fox, David T.; Goodenough, Ursula; Jaworski, Jan; Holladay, Jonathan E.; Kramer, David M.; Koppisch, Andrew T; Lipton, Mary S.; Marrone, Babetta L.; McCormick, Margaret; Molnár, István; Mott, John B.; Ogden, Kimberly L.; Panisko, Ellen A.; Pellegrini, Matteo; Polle, Juergen; Richardson, James W.; Sabarsky, Martin; Starkenburg, Shawn R.; Stormo, Gary D.; Teshima, Munehiro; Twary, Scott N.; Unkefer, Pat J.; Yuan, Joshua S.; Olivares, José A.

In: Algal Research, Vol. 22, 01.03.2017, p. 187-215.

Research output: Contribution to journalArticle

Unkefer, CJ, Sayre, RT, Magnuson, JK, Anderson, DB, Baxter, I, Blaby, IK, Brown, JK, Carleton, M, Cattolico, RA, Dale, T, Devarenne, TP, Downes, CM, Dutcher, SK, Fox, DT, Goodenough, U, Jaworski, J, Holladay, JE, Kramer, DM, Koppisch, AT, Lipton, MS, Marrone, BL, McCormick, M, Molnár, I, Mott, JB, Ogden, KL, Panisko, EA, Pellegrini, M, Polle, J, Richardson, JW, Sabarsky, M, Starkenburg, SR, Stormo, GD, Teshima, M, Twary, SN, Unkefer, PJ, Yuan, JS & Olivares, JA 2017, 'Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts', Algal Research, vol. 22, pp. 187-215. https://doi.org/10.1016/j.algal.2016.06.002
Unkefer, Clifford J. ; Sayre, Richard T. ; Magnuson, Jon K. ; Anderson, Daniel B. ; Baxter, Ivan ; Blaby, Ian K. ; Brown, Judith K. ; Carleton, Michael ; Cattolico, Rose Ann ; Dale, Taraka ; Devarenne, Timothy P. ; Downes, C. Meghan ; Dutcher, Susan K. ; Fox, David T. ; Goodenough, Ursula ; Jaworski, Jan ; Holladay, Jonathan E. ; Kramer, David M. ; Koppisch, Andrew T ; Lipton, Mary S. ; Marrone, Babetta L. ; McCormick, Margaret ; Molnár, István ; Mott, John B. ; Ogden, Kimberly L. ; Panisko, Ellen A. ; Pellegrini, Matteo ; Polle, Juergen ; Richardson, James W. ; Sabarsky, Martin ; Starkenburg, Shawn R. ; Stormo, Gary D. ; Teshima, Munehiro ; Twary, Scott N. ; Unkefer, Pat J. ; Yuan, Joshua S. ; Olivares, José A. / Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts. In: Algal Research. 2017 ; Vol. 22. pp. 187-215.
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