Pathogen dynamics during invasion and establishment of white-nose syndrome explain mechanisms of host persistence

Winifred F. Frick, Tina L. Cheng, Kate E. Langwig, Joseph R. Hoyt, Amanda F. Janicki, Katy L. Parise, Jeffrey T Foster, A. Marm Kilpatrick

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Disease dynamics during pathogen invasion and establishment determine the impacts of disease on host populations and determine the mechanisms of host persistence. Temporal progression of prevalence and infection intensity illustrate whether tolerance, resistance, reduced transmission, or demographic compensation allow initially declining populations to persist. We measured infection dynamics of the fungal pathogen Pseudogymnoascus destructans that causes white-nose syndrome in bats by estimating pathogen prevalence and load in seven bat species at 167 hibernacula over a decade as the pathogen invaded, became established, and some host populations stabilized. Fungal loads increased rapidly and prevalence rose to nearly 100% at most sites within 2 yr of invasion in six of seven species. Prevalence and loads did not decline over time despite huge reductions in colony sizes, likely due to an extensive environmental reservoir. However, there was substantial variation in fungal load among sites with persisting colonies, suggesting that both tolerance and resistance developed at different sites in the same species. In contrast, one species disappeared from hibernacula within 3 yr of pathogen invasion. Variable host responses to pathogen invasion require different management strategies to prevent disease-induced extinction and to facilitate evolution of tolerance or resistance in persisting populations.

Original languageEnglish (US)
Pages (from-to)624-631
Number of pages8
JournalEcology
Volume98
Issue number3
DOIs
StatePublished - Mar 1 2017

Fingerprint

persistence
pathogen
pathogens
tolerance
hibernation
bat
Chiroptera
infection
white-nose syndrome
Rosa
extinction
demographic statistics

Keywords

  • Extinction
  • Geomyces
  • Invasive species
  • Pseudogymnoascus destructans
  • White-nose syndrome
  • Wildlife disease

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics

Cite this

Frick, W. F., Cheng, T. L., Langwig, K. E., Hoyt, J. R., Janicki, A. F., Parise, K. L., ... Kilpatrick, A. M. (2017). Pathogen dynamics during invasion and establishment of white-nose syndrome explain mechanisms of host persistence. Ecology, 98(3), 624-631. https://doi.org/10.1002/ecy.1706/suppinfo

Pathogen dynamics during invasion and establishment of white-nose syndrome explain mechanisms of host persistence. / Frick, Winifred F.; Cheng, Tina L.; Langwig, Kate E.; Hoyt, Joseph R.; Janicki, Amanda F.; Parise, Katy L.; Foster, Jeffrey T; Kilpatrick, A. Marm.

In: Ecology, Vol. 98, No. 3, 01.03.2017, p. 624-631.

Research output: Contribution to journalArticle

Frick, WF, Cheng, TL, Langwig, KE, Hoyt, JR, Janicki, AF, Parise, KL, Foster, JT & Kilpatrick, AM 2017, 'Pathogen dynamics during invasion and establishment of white-nose syndrome explain mechanisms of host persistence', Ecology, vol. 98, no. 3, pp. 624-631. https://doi.org/10.1002/ecy.1706/suppinfo
Frick, Winifred F. ; Cheng, Tina L. ; Langwig, Kate E. ; Hoyt, Joseph R. ; Janicki, Amanda F. ; Parise, Katy L. ; Foster, Jeffrey T ; Kilpatrick, A. Marm. / Pathogen dynamics during invasion and establishment of white-nose syndrome explain mechanisms of host persistence. In: Ecology. 2017 ; Vol. 98, No. 3. pp. 624-631.
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