Highly efficient trapping of the Nazarov intermediate with substituted arenes

Cindy C. Browder, Fredrik P. Marmsäter, F. G. West

Research output: Contribution to journalArticle

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Abstract

matrix presented 1,4-Dien-3-ones bearing pendant arylethyl side chains were readily prepared from substituted dihydrocinnamaldehydes. When treated with TiCl4 at low temperature, these compounds underwent domino cyclization to give benzohydrindenones in near-quantitative yield and with complete diastereoselectivity.

Original languageEnglish (US)
Pages (from-to)3033-3035
Number of pages3
JournalOrganic Letters
Volume3
Issue number19
DOIs
StatePublished - Sep 20 2001

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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