Highly efficient trapping of the Nazarov intermediate with substituted arenes

Cindy C Browder, Fredrik P. Marmsäter, F. G. West

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

matrix presented 1,4-Dien-3-ones bearing pendant arylethyl side chains were readily prepared from substituted dihydrocinnamaldehydes. When treated with TiCl4 at low temperature, these compounds underwent domino cyclization to give benzohydrindenones in near-quantitative yield and with complete diastereoselectivity.

Original languageEnglish (US)
Pages (from-to)3033-3035
Number of pages3
JournalOrganic Letters
Volume3
Issue number19
DOIs
StatePublished - Sep 20 2001
Externally publishedYes

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Bearings (structural)
Cyclization
trapping
Temperature
matrices
titanium tetrachloride

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Highly efficient trapping of the Nazarov intermediate with substituted arenes. / Browder, Cindy C; Marmsäter, Fredrik P.; West, F. G.

In: Organic Letters, Vol. 3, No. 19, 20.09.2001, p. 3033-3035.

Research output: Contribution to journalArticle

Browder, Cindy C ; Marmsäter, Fredrik P. ; West, F. G. / Highly efficient trapping of the Nazarov intermediate with substituted arenes. In: Organic Letters. 2001 ; Vol. 3, No. 19. pp. 3033-3035.
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