Geography and location are the primary drivers of office microbiome composition

John Chase, Jennifer Fouquier, Mahnaz Zare, Derek L Sonderegger, Rob Knight, Scott T. Kelley, Jeffrey Siegel, James G Caporaso

Research output: Contribution to journalReview article

39 Citations (Scopus)

Abstract

In the United States, humans spend the majority of their time indoors, where they are exposed to the microbiome of the built environment (BE) they inhabit. Despite the ubiquity of microbes in BEs and their potential impacts on health and building materials, basic questions about the microbiology of these environments remain unanswered. We present a study on the impacts of geography, material type, human interaction, location in a room, seasonal variation, and indoor and microenvironmental parameters on bacterial communities in offices. Our data elucidate several important features of microbial communities in BEs. First, under normal office environmental conditions, bacterial communities do not differ on the basis of surface material (e.g., ceiling tile or carpet) but do differ on the basis of the location in a room (e.g., ceiling or floor), two features that are often conflated but that we are able to separate here. We suspect that previous work showing differences in bacterial composition with surface material was likely detecting differences based on different usage patterns. Next, we find that offices have city-specific bacterial communities, such that we can accurately predict which city an office microbiome sample is derived from, but office-specific bacterial communities are less apparent. This differs from previous work, which has suggested office-specific compositions of bacterial communities. We again suspect that the difference from prior work arises from different usage patterns. As has been previously shown, we observe that human skin contributes heavily to the composition of BE surfaces.

Original languageEnglish (US)
Article numbere00022-16
JournalmSystems
Volume1
Issue number2
DOIs
StatePublished - Mar 1 2016

Fingerprint

Geography
Microbiota
geography
bacterial communities
Driver
Ceilings
Microbiology
Chemical analysis
Ceiling
Tile
Skin
Health
tiles
microbiology
skin (animal)
microbial communities
seasonal variation
Community
microbiome
office

Keywords

  • Bacteria
  • Built environment
  • Fungi
  • Microbiome

ASJC Scopus subject areas

  • Molecular Biology
  • Physiology
  • Genetics
  • Biochemistry
  • Modeling and Simulation
  • Computer Science Applications
  • Ecology, Evolution, Behavior and Systematics
  • Microbiology

Cite this

Geography and location are the primary drivers of office microbiome composition. / Chase, John; Fouquier, Jennifer; Zare, Mahnaz; Sonderegger, Derek L; Knight, Rob; Kelley, Scott T.; Siegel, Jeffrey; Caporaso, James G.

In: mSystems, Vol. 1, No. 2, e00022-16, 01.03.2016.

Research output: Contribution to journalReview article

Chase, John ; Fouquier, Jennifer ; Zare, Mahnaz ; Sonderegger, Derek L ; Knight, Rob ; Kelley, Scott T. ; Siegel, Jeffrey ; Caporaso, James G. / Geography and location are the primary drivers of office microbiome composition. In: mSystems. 2016 ; Vol. 1, No. 2.
@article{2d8c121aff7b41a893a68fc2418d0d89,
title = "Geography and location are the primary drivers of office microbiome composition",
abstract = "In the United States, humans spend the majority of their time indoors, where they are exposed to the microbiome of the built environment (BE) they inhabit. Despite the ubiquity of microbes in BEs and their potential impacts on health and building materials, basic questions about the microbiology of these environments remain unanswered. We present a study on the impacts of geography, material type, human interaction, location in a room, seasonal variation, and indoor and microenvironmental parameters on bacterial communities in offices. Our data elucidate several important features of microbial communities in BEs. First, under normal office environmental conditions, bacterial communities do not differ on the basis of surface material (e.g., ceiling tile or carpet) but do differ on the basis of the location in a room (e.g., ceiling or floor), two features that are often conflated but that we are able to separate here. We suspect that previous work showing differences in bacterial composition with surface material was likely detecting differences based on different usage patterns. Next, we find that offices have city-specific bacterial communities, such that we can accurately predict which city an office microbiome sample is derived from, but office-specific bacterial communities are less apparent. This differs from previous work, which has suggested office-specific compositions of bacterial communities. We again suspect that the difference from prior work arises from different usage patterns. As has been previously shown, we observe that human skin contributes heavily to the composition of BE surfaces.",
keywords = "Bacteria, Built environment, Fungi, Microbiome",
author = "John Chase and Jennifer Fouquier and Mahnaz Zare and Sonderegger, {Derek L} and Rob Knight and Kelley, {Scott T.} and Jeffrey Siegel and Caporaso, {James G}",
year = "2016",
month = "3",
day = "1",
doi = "10.1128/mSystems.00022-16",
language = "English (US)",
volume = "1",
journal = "mSystems",
issn = "2379-5077",
publisher = "American Society for Microbiology",
number = "2",

}

TY - JOUR

T1 - Geography and location are the primary drivers of office microbiome composition

AU - Chase, John

AU - Fouquier, Jennifer

AU - Zare, Mahnaz

AU - Sonderegger, Derek L

AU - Knight, Rob

AU - Kelley, Scott T.

AU - Siegel, Jeffrey

AU - Caporaso, James G

PY - 2016/3/1

Y1 - 2016/3/1

N2 - In the United States, humans spend the majority of their time indoors, where they are exposed to the microbiome of the built environment (BE) they inhabit. Despite the ubiquity of microbes in BEs and their potential impacts on health and building materials, basic questions about the microbiology of these environments remain unanswered. We present a study on the impacts of geography, material type, human interaction, location in a room, seasonal variation, and indoor and microenvironmental parameters on bacterial communities in offices. Our data elucidate several important features of microbial communities in BEs. First, under normal office environmental conditions, bacterial communities do not differ on the basis of surface material (e.g., ceiling tile or carpet) but do differ on the basis of the location in a room (e.g., ceiling or floor), two features that are often conflated but that we are able to separate here. We suspect that previous work showing differences in bacterial composition with surface material was likely detecting differences based on different usage patterns. Next, we find that offices have city-specific bacterial communities, such that we can accurately predict which city an office microbiome sample is derived from, but office-specific bacterial communities are less apparent. This differs from previous work, which has suggested office-specific compositions of bacterial communities. We again suspect that the difference from prior work arises from different usage patterns. As has been previously shown, we observe that human skin contributes heavily to the composition of BE surfaces.

AB - In the United States, humans spend the majority of their time indoors, where they are exposed to the microbiome of the built environment (BE) they inhabit. Despite the ubiquity of microbes in BEs and their potential impacts on health and building materials, basic questions about the microbiology of these environments remain unanswered. We present a study on the impacts of geography, material type, human interaction, location in a room, seasonal variation, and indoor and microenvironmental parameters on bacterial communities in offices. Our data elucidate several important features of microbial communities in BEs. First, under normal office environmental conditions, bacterial communities do not differ on the basis of surface material (e.g., ceiling tile or carpet) but do differ on the basis of the location in a room (e.g., ceiling or floor), two features that are often conflated but that we are able to separate here. We suspect that previous work showing differences in bacterial composition with surface material was likely detecting differences based on different usage patterns. Next, we find that offices have city-specific bacterial communities, such that we can accurately predict which city an office microbiome sample is derived from, but office-specific bacterial communities are less apparent. This differs from previous work, which has suggested office-specific compositions of bacterial communities. We again suspect that the difference from prior work arises from different usage patterns. As has been previously shown, we observe that human skin contributes heavily to the composition of BE surfaces.

KW - Bacteria

KW - Built environment

KW - Fungi

KW - Microbiome

UR - http://www.scopus.com/inward/record.url?scp=84991275504&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991275504&partnerID=8YFLogxK

U2 - 10.1128/mSystems.00022-16

DO - 10.1128/mSystems.00022-16

M3 - Review article

AN - SCOPUS:84991275504

VL - 1

JO - mSystems

JF - mSystems

SN - 2379-5077

IS - 2

M1 - e00022-16

ER -