Fine-scale identification of the most likely source of a human plague infection

Rebecca E. Colman, Amy J. Vogler, Jennifer L. Lowell, Kenneth L. Gage, Christina Morway, Pamela J. Reynolds, Paul Ettestad, Paul Keim, Michael Y. Kosoy, David M. Wagner

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the utility of this approach using data from a North American human plague investigation.

Original languageEnglish (US)
Pages (from-to)1623-1625
Number of pages3
JournalEmerging infectious diseases
Volume15
Issue number10
DOIs
StatePublished - Oct 2009

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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