Fiber size and myosin phenotypes of selected rhesus lower limb muscles after a 14-day spaceflight.

R. R. Roy, H. Zhong, S. C. Bodine, David J Pierotti, R. J. Talmadge, G. Barkhoudarian, J. Kim, J. W. Fanton, I. B. Kozlovskaya, V. R. Edgerton

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Muscle biopsies were taken from the rhesus (Macaca mulatta) soleus (Sol, a slow ankle extensor), medial gastrocnemius (MG, a fast ankle extensor), tibialis anterior (TA, a fast ankle flexor), and vastus lateralis (VL, a fast knee extensor) muscles in vivarium controls (n=5) before and after either a 14-day spaceflight (Bion 11, n=2) or a 14-day ground-based flight simulation (n=3). Myosin heavy chain (MHC) composition (gel electrophoresis), fiber type distribution (immunohistochemistry), and fiber size were determined. Although there were no significant changes, each muscle showed trends towards adaptation.

Original languageEnglish (US)
JournalJournal of gravitational physiology : a journal of the International Society for Gravitational Physiology
Volume7
Issue number1
StatePublished - 2000
Externally publishedYes

Fingerprint

Space Flight
Myosins
Ankle
Lower Extremity
Phenotype
Muscles
Myosin Heavy Chains
Quadriceps Muscle
Polymethyl Methacrylate
Macaca mulatta
Electrophoresis
Knee
Gels
Immunohistochemistry
Biopsy

Cite this

Fiber size and myosin phenotypes of selected rhesus lower limb muscles after a 14-day spaceflight. / Roy, R. R.; Zhong, H.; Bodine, S. C.; Pierotti, David J; Talmadge, R. J.; Barkhoudarian, G.; Kim, J.; Fanton, J. W.; Kozlovskaya, I. B.; Edgerton, V. R.

In: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, Vol. 7, No. 1, 2000.

Research output: Contribution to journalArticle

Roy, R. R. ; Zhong, H. ; Bodine, S. C. ; Pierotti, David J ; Talmadge, R. J. ; Barkhoudarian, G. ; Kim, J. ; Fanton, J. W. ; Kozlovskaya, I. B. ; Edgerton, V. R. / Fiber size and myosin phenotypes of selected rhesus lower limb muscles after a 14-day spaceflight. In: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology. 2000 ; Vol. 7, No. 1.
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AU - Zhong, H.

AU - Bodine, S. C.

AU - Pierotti, David J

AU - Talmadge, R. J.

AU - Barkhoudarian, G.

AU - Kim, J.

AU - Fanton, J. W.

AU - Kozlovskaya, I. B.

AU - Edgerton, V. R.

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