Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks

H. Shams, F. L. Powell, S. C. Hempleman

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.

Original languageEnglish (US)
Pages (from-to)163-170
Number of pages8
JournalRespiration Physiology
Volume80
Issue number2-3
DOIs
StatePublished - 1990
Externally publishedYes

Fingerprint

Ducks
Ventilation
Gases
Pressure
Tidal Volume
Oceans and Seas
Hypoxia

Keywords

  • Aerodynamic valving
  • Airflow, airways of birds
  • Airway, airway in
  • Altitude, bird respiration
  • Animal, birds
  • bird lungs
  • Hypoxia, bird respiration

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine

Cite this

Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks. / Shams, H.; Powell, F. L.; Hempleman, S. C.

In: Respiration Physiology, Vol. 80, No. 2-3, 1990, p. 163-170.

Research output: Contribution to journalArticle

@article{62fbf84b76f04c73838aa6941ddf704f,
title = "Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks",
abstract = "We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21{\%} O2 (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.",
keywords = "Aerodynamic valving, Airflow, airways of birds, Airway, airway in, Altitude, bird respiration, Animal, birds, bird lungs, Hypoxia, bird respiration",
author = "H. Shams and Powell, {F. L.} and Hempleman, {S. C.}",
year = "1990",
doi = "10.1016/0034-5687(90)90080-I",
language = "English (US)",
volume = "80",
pages = "163--170",
journal = "Respiratory Physiology and Neurobiology",
issn = "1569-9048",
publisher = "Elsevier",
number = "2-3",

}

TY - JOUR

T1 - Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks

AU - Shams, H.

AU - Powell, F. L.

AU - Hempleman, S. C.

PY - 1990

Y1 - 1990

N2 - We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.

AB - We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.

KW - Aerodynamic valving

KW - Airflow, airways of birds

KW - Airway, airway in

KW - Altitude, bird respiration

KW - Animal, birds

KW - bird lungs

KW - Hypoxia, bird respiration

UR - http://www.scopus.com/inward/record.url?scp=0025316126&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025316126&partnerID=8YFLogxK

U2 - 10.1016/0034-5687(90)90080-I

DO - 10.1016/0034-5687(90)90080-I

M3 - Article

C2 - 2218098

AN - SCOPUS:0025316126

VL - 80

SP - 163

EP - 170

JO - Respiratory Physiology and Neurobiology

JF - Respiratory Physiology and Neurobiology

SN - 1569-9048

IS - 2-3

ER -