Dogs are more permissive than cats or guinea pigs to experimental infection with a human isolate of Bartonella rochalimae

Bruno B. Chomel, Jennifer B. Henn, Rickie W. Kasten, Nathan C Nieto, Janet Foley, Sophia Papageorgiou, Claire Allen, Jane E. Koehler

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Bartonella rochalimae was first isolated from the blood of a human who traveled to Peru and was exposed to multiple insect bites. Foxes and dogs are likely natural reservoirs for this bacterium. We report the results of experimental inoculation of two dogs, five cats and six guinea pigs with the only human isolate of this new Bartonella species. Both dogs became bacteremic for 5-7 weeks, with a peak of 10-10 colony forming units (CFU)/mL blood. Three cats had low bacteremia levels ( 200 CFU/mL) of 6-8 weeks' duration. One cat that remained seronegative had two bacterial colonies isolated at a single culture time point. A fifth cat never became bacteremic, but seroconverted. None of the guinea pigs became bacteremic, but five seroconverted. These results suggest that dogs could be a reservoir of this strain of B. rochalimae, in contrast to cats and guinea pigs.

Original languageEnglish (US)
Article number27
JournalVeterinary Research
Volume40
Issue number4
DOIs
StatePublished - Jul 2009
Externally publishedYes

Fingerprint

Bartonella
guinea pigs
Guinea Pigs
Cats
Dogs
cats
dogs
Infection
infection
Stem Cells
Insect Bites and Stings
bacteremia
Peru
blood
Bacteremia
foxes
Bacteria
insects
duration
bacteria

Keywords

  • Bartonella rochalimae
  • Cats
  • Dogs
  • Guinea pigs
  • Zoonosis

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Dogs are more permissive than cats or guinea pigs to experimental infection with a human isolate of Bartonella rochalimae. / Chomel, Bruno B.; Henn, Jennifer B.; Kasten, Rickie W.; Nieto, Nathan C; Foley, Janet; Papageorgiou, Sophia; Allen, Claire; Koehler, Jane E.

In: Veterinary Research, Vol. 40, No. 4, 27, 07.2009.

Research output: Contribution to journalArticle

Chomel, Bruno B. ; Henn, Jennifer B. ; Kasten, Rickie W. ; Nieto, Nathan C ; Foley, Janet ; Papageorgiou, Sophia ; Allen, Claire ; Koehler, Jane E. / Dogs are more permissive than cats or guinea pigs to experimental infection with a human isolate of Bartonella rochalimae. In: Veterinary Research. 2009 ; Vol. 40, No. 4.
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