Disease risk & landscape attributes of tick-borne Borrelia pathogens in the San Francisco Bay Area, California

Daniel J. Salkeld, Nathan C Nieto, Patricia Carbajales-Dale, Michael Carbajales-Dale, Stephanie S. Cinkovich, Eric F. Lambin

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Habitat heterogeneity influences pathogen ecology by affecting vector abundance and the reservoir host communities. We investigated spatial patterns of disease risk for two human pathogens in the Borrelia genus-B. burgdorferi and B. miyamotoi-that are transmitted by the western black-legged tick, Ixodes pacificus. We collected ticks (349 nymphs, 273 adults) at 20 sites in the San Francisco Bay Area, California, USA. Tick abundance, pathogen prevalence and density of infected nymphs varied widely across sites and habitat type, though nymphal western black-legged ticks were more frequently found, and were more abundant in coast live oak forest and desert/semi-desert scrub (dominated by California sagebrush) habitats. We observed Borrelia infections in ticks at all sites where we able to collect >10 ticks. The recently recognized human pathogen, B. miyamotoi, was observed at a higher prevalence (13/349 nymphs = 3.7%, 95% CI = 2.0-6.3; 5/273 adults = 1.8%, 95% CI = 0.6-4.2) than recent studies from nearby locations (Alameda County, east of the San Francisco Bay), demonstrating that tick-borne disease risk and ecology can vary substantially at small geographic scales, with consequences for public health and disease diagnosis.

Original languageEnglish (US)
Article numbere0134812
JournalPLoS One
Volume10
Issue number8
DOIs
StatePublished - Aug 19 2015

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Borrelia
San Francisco
Ixodes pacificus
Ticks
Pathogens
Nymph
Ixodes
Borrelia miyamotoi
ticks
nymphs
Ecosystem
pathogens
Ecology
deserts
habitats
Quercus agrifolia
Borrelia Infections
Tick-Borne Diseases
ecology
Artemisia

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Salkeld, D. J., Nieto, N. C., Carbajales-Dale, P., Carbajales-Dale, M., Cinkovich, S. S., & Lambin, E. F. (2015). Disease risk & landscape attributes of tick-borne Borrelia pathogens in the San Francisco Bay Area, California. PLoS One, 10(8), [e0134812]. https://doi.org/10.1371/journal.pone.0134812

Disease risk & landscape attributes of tick-borne Borrelia pathogens in the San Francisco Bay Area, California. / Salkeld, Daniel J.; Nieto, Nathan C; Carbajales-Dale, Patricia; Carbajales-Dale, Michael; Cinkovich, Stephanie S.; Lambin, Eric F.

In: PLoS One, Vol. 10, No. 8, e0134812, 19.08.2015.

Research output: Contribution to journalArticle

Salkeld, DJ, Nieto, NC, Carbajales-Dale, P, Carbajales-Dale, M, Cinkovich, SS & Lambin, EF 2015, 'Disease risk & landscape attributes of tick-borne Borrelia pathogens in the San Francisco Bay Area, California', PLoS One, vol. 10, no. 8, e0134812. https://doi.org/10.1371/journal.pone.0134812
Salkeld, Daniel J. ; Nieto, Nathan C ; Carbajales-Dale, Patricia ; Carbajales-Dale, Michael ; Cinkovich, Stephanie S. ; Lambin, Eric F. / Disease risk & landscape attributes of tick-borne Borrelia pathogens in the San Francisco Bay Area, California. In: PLoS One. 2015 ; Vol. 10, No. 8.
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