Conducting a microbiome study

Julia K. Goodrich, Sara C. Di Rienzi, Angela C. Poole, Omry Koren, William A. Walters, J. Gregory Caporaso, Rob Knight, Ruth E. Ley

Research output: Contribution to journalReview article

277 Scopus citations

Abstract

Human microbiome research is an actively developing area of inquiry, with ramifications for our lifestyles, our interactions with microbes, and how we treat disease. Advances depend on carefully executed, controlled, and reproducible studies. Here, we provide a Primer for researchers from diverse disciplines interested in conducting microbiome research. We discuss factors to be considered in the design, execution, and data analysis of microbiome studies. These recommendations should help researchers to enter and contribute to this rapidly developing field.

Original languageEnglish (US)
Pages (from-to)250-262
Number of pages13
JournalCell
Volume158
Issue number2
DOIs
StatePublished - Jul 17 2014

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Goodrich, J. K., Di Rienzi, S. C., Poole, A. C., Koren, O., Walters, W. A., Caporaso, J. G., Knight, R., & Ley, R. E. (2014). Conducting a microbiome study. Cell, 158(2), 250-262. https://doi.org/10.1016/j.cell.2014.06.037