Comparative toxicity of some naturally occurring and synthetic non-protein amino acids

Dushyant K. Gulati, Carol L Chambers, Gerald A. Rosenthal, P. S. Sabharwal

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Evaluation of the comparative toxicity of 55 non-protein amino acids, in terms of their effect on growth of Lemna minor, revealed that these compounds possess a wide diversity in their growth-inhibiting ability. Replacement of the sulphur atom by selenium in protein amino acids and certain fluoro-substitution was toxic. Addition of a methyl or phenyl group to the carbon skeleton of an individual protein amino acid did not affect Lemna growth. The tested amino acids were arranged in order of their decreasing toxicity and, for convenience, were divided into five groups based on their relative toxicity. Group I included the most disruptive secondary amino acids and members of Group II and III exhibited an intermediate growth inhibiting capacity. Slightly toxic secondary amino acids and compounds which had no discernible effect on Lemna growth were placed in Group IV and V, respectively.

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalEnvironmental and Experimental Botany
Volume21
Issue number2
DOIs
StatePublished - 1981
Externally publishedYes

Fingerprint

nonprotein amino acids
Lemna
amino acid
toxicity
amino acids
amino compounds
Lemna minor
selenium
skeleton
sulfur
proteins
protein
carbon
substitution
replacement
imino acids

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Plant Science
  • Environmental Science(all)

Cite this

Comparative toxicity of some naturally occurring and synthetic non-protein amino acids. / Gulati, Dushyant K.; Chambers, Carol L; Rosenthal, Gerald A.; Sabharwal, P. S.

In: Environmental and Experimental Botany, Vol. 21, No. 2, 1981, p. 225-230.

Research output: Contribution to journalArticle

Gulati, Dushyant K. ; Chambers, Carol L ; Rosenthal, Gerald A. ; Sabharwal, P. S. / Comparative toxicity of some naturally occurring and synthetic non-protein amino acids. In: Environmental and Experimental Botany. 1981 ; Vol. 21, No. 2. pp. 225-230.
@article{c4e49319c217495984ee1872022e8dc4,
title = "Comparative toxicity of some naturally occurring and synthetic non-protein amino acids",
abstract = "Evaluation of the comparative toxicity of 55 non-protein amino acids, in terms of their effect on growth of Lemna minor, revealed that these compounds possess a wide diversity in their growth-inhibiting ability. Replacement of the sulphur atom by selenium in protein amino acids and certain fluoro-substitution was toxic. Addition of a methyl or phenyl group to the carbon skeleton of an individual protein amino acid did not affect Lemna growth. The tested amino acids were arranged in order of their decreasing toxicity and, for convenience, were divided into five groups based on their relative toxicity. Group I included the most disruptive secondary amino acids and members of Group II and III exhibited an intermediate growth inhibiting capacity. Slightly toxic secondary amino acids and compounds which had no discernible effect on Lemna growth were placed in Group IV and V, respectively.",
author = "Gulati, {Dushyant K.} and Chambers, {Carol L} and Rosenthal, {Gerald A.} and Sabharwal, {P. S.}",
year = "1981",
doi = "10.1016/0098-8472(81)90029-0",
language = "English (US)",
volume = "21",
pages = "225--230",
journal = "Environmental and Experimental Botany",
issn = "0098-8472",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Comparative toxicity of some naturally occurring and synthetic non-protein amino acids

AU - Gulati, Dushyant K.

AU - Chambers, Carol L

AU - Rosenthal, Gerald A.

AU - Sabharwal, P. S.

PY - 1981

Y1 - 1981

N2 - Evaluation of the comparative toxicity of 55 non-protein amino acids, in terms of their effect on growth of Lemna minor, revealed that these compounds possess a wide diversity in their growth-inhibiting ability. Replacement of the sulphur atom by selenium in protein amino acids and certain fluoro-substitution was toxic. Addition of a methyl or phenyl group to the carbon skeleton of an individual protein amino acid did not affect Lemna growth. The tested amino acids were arranged in order of their decreasing toxicity and, for convenience, were divided into five groups based on their relative toxicity. Group I included the most disruptive secondary amino acids and members of Group II and III exhibited an intermediate growth inhibiting capacity. Slightly toxic secondary amino acids and compounds which had no discernible effect on Lemna growth were placed in Group IV and V, respectively.

AB - Evaluation of the comparative toxicity of 55 non-protein amino acids, in terms of their effect on growth of Lemna minor, revealed that these compounds possess a wide diversity in their growth-inhibiting ability. Replacement of the sulphur atom by selenium in protein amino acids and certain fluoro-substitution was toxic. Addition of a methyl or phenyl group to the carbon skeleton of an individual protein amino acid did not affect Lemna growth. The tested amino acids were arranged in order of their decreasing toxicity and, for convenience, were divided into five groups based on their relative toxicity. Group I included the most disruptive secondary amino acids and members of Group II and III exhibited an intermediate growth inhibiting capacity. Slightly toxic secondary amino acids and compounds which had no discernible effect on Lemna growth were placed in Group IV and V, respectively.

UR - http://www.scopus.com/inward/record.url?scp=0010469685&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0010469685&partnerID=8YFLogxK

U2 - 10.1016/0098-8472(81)90029-0

DO - 10.1016/0098-8472(81)90029-0

M3 - Article

VL - 21

SP - 225

EP - 230

JO - Environmental and Experimental Botany

JF - Environmental and Experimental Botany

SN - 0098-8472

IS - 2

ER -