Cohabiting family members share microbiota with one another and with their dogs

Se Jin Song, Christian Lauber, Elizabeth K. Costello, Catherine A. Lozupone, Gregory Humphrey, Donna Berg-Lyons, James G Caporaso, Dan Knights, Jose C. Clemente, Sara Nakielny, Jeffrey I. Gordon, Noah Fierer, Rob Knight

Research output: Contribution to journalArticle

331 Citations (Scopus)

Abstract

Human-associated microbial communities vary across individuals: possible contributing factors include (genetic) relatedness, diet, and age. However, our surroundings, including individuals with whom we interact, also likely shape our microbial communities. To quantify this microbial exchange, we surveyed fecal, oral, and skin microbiota from 60 families (spousal units with children, dogs, both, or neither). Household members, particularly couples, shared more of their microbiota than individuals from different households, with stronger effects of co-habitation on skin than oral or fecal microbiota. Dog ownership significantly increased the shared skin microbiota in cohabiting adults, and dog-owning adults shared more 'skin' microbiota with their own dogs than with other dogs. Although the degree to which these shared microbes have a true niche on the human body, vs transient detection after direct contact, is unknown, these results suggest that direct and frequent contact with our cohabitants may significantly shape the composition of our microbial communities.

Original languageEnglish (US)
Article numbere00458
JournaleLife
Volume2013
Issue number2
DOIs
StatePublished - Apr 16 2013

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Microbiota
Skin
Dogs
Nutrition
Ownership
Human Body
Diet
Chemical analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)
  • Neuroscience(all)

Cite this

Song, S. J., Lauber, C., Costello, E. K., Lozupone, C. A., Humphrey, G., Berg-Lyons, D., ... Knight, R. (2013). Cohabiting family members share microbiota with one another and with their dogs. eLife, 2013(2), [e00458]. https://doi.org/10.7554/eLife.00458

Cohabiting family members share microbiota with one another and with their dogs. / Song, Se Jin; Lauber, Christian; Costello, Elizabeth K.; Lozupone, Catherine A.; Humphrey, Gregory; Berg-Lyons, Donna; Caporaso, James G; Knights, Dan; Clemente, Jose C.; Nakielny, Sara; Gordon, Jeffrey I.; Fierer, Noah; Knight, Rob.

In: eLife, Vol. 2013, No. 2, e00458, 16.04.2013.

Research output: Contribution to journalArticle

Song, SJ, Lauber, C, Costello, EK, Lozupone, CA, Humphrey, G, Berg-Lyons, D, Caporaso, JG, Knights, D, Clemente, JC, Nakielny, S, Gordon, JI, Fierer, N & Knight, R 2013, 'Cohabiting family members share microbiota with one another and with their dogs', eLife, vol. 2013, no. 2, e00458. https://doi.org/10.7554/eLife.00458
Song SJ, Lauber C, Costello EK, Lozupone CA, Humphrey G, Berg-Lyons D et al. Cohabiting family members share microbiota with one another and with their dogs. eLife. 2013 Apr 16;2013(2). e00458. https://doi.org/10.7554/eLife.00458
Song, Se Jin ; Lauber, Christian ; Costello, Elizabeth K. ; Lozupone, Catherine A. ; Humphrey, Gregory ; Berg-Lyons, Donna ; Caporaso, James G ; Knights, Dan ; Clemente, Jose C. ; Nakielny, Sara ; Gordon, Jeffrey I. ; Fierer, Noah ; Knight, Rob. / Cohabiting family members share microbiota with one another and with their dogs. In: eLife. 2013 ; Vol. 2013, No. 2.
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