Avian arterial chemoreceptor responses to steps of CO2 and O2

S. C. Hempleman, F. L. Powell, G. K. Prisk

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

The responses of avian arterial chemoreceptor preparations to 44-sec steps of inspired CO2 and O2 were quantified. Anesthetized ducks were unidirectionally ventilated, arterial pH was recorded with a fast responding indwelling electrode, and neural activity was recorded from 28 preparations consisting of dissected filaments of the vagus nerve (23 single-fibered, 5 few-fibered). We analyzed responses using cycle-triggered stimulus histograms of neural discharge, cross correlation analysis, and analysis of variance. Average responses of the chemoreceptor preparations to PaCO2 steps from 24 ± 1 to 38 ± 1 Torr were larger (per 56 ± 2 Torr. Average responses to CO2 steps usually appeared more rate sensitive when measured during arterial hypoxia than during arterial normoxia. These characteristics are very much like those reported for mammalian arterial chemoreceptors, except that responses of avian chemoreceptor preparations to repetitive CO2 steps were highly variable according to statistical analysis.

Original languageEnglish (US)
Pages (from-to)325-340
Number of pages16
JournalRespiration Physiology
Volume90
Issue number3
DOIs
StatePublished - Dec 1992
Externally publishedYes

Keywords

  • Birds, duck
  • Carotid body, sensitivity CO, O steps
  • Control of breathing, arterial chemoreceptors
  • Receptors, arterial chemo

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine

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