A model of the interaction between O2 and CO2 exchange and cardiopulmonary control in the duck

S. C. Hempleman, W. L. Sexton, M. R. Barker, R. E. Burger

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A simple model was used to predict resting blood gases and ventilation of ducks at sea level and at altitude. Unique features of the gas exchange model were the use of (1) empirical hyperbolic equations to predict the CO2 content of blood and plasma, (2) plasma CO2 content and PCO2 to predict the pH-dependent hemoglobin affinity for O2 and (3) gas contents in the mass balance equations. We utilized literature data to describe ventilatory sensitivity to blood gases and the relation of arterial-venous oxygen content differences to blood flow. The model predicted values within 4% of observations.

Original languageEnglish (US)
Pages (from-to)167-178
Number of pages12
JournalComputers in Biology and Medicine
Volume9
Issue number3
DOIs
StatePublished - 1979
Externally publishedYes

Keywords

  • Avian respiration
  • Bohr effect
  • Cross current exchange
  • Dissociation curves
  • Hemoglobin
  • Hypoxia
  • Parabronchus
  • Simulation
  • Ventilation-perfusion
  • Ventilatory sensitivity

ASJC Scopus subject areas

  • Computer Science Applications
  • Health Informatics

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