Projects per year
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Ligands
Medicine & Life Sciences
Immunoglobulin E
Medicine & Life Sciences
Receptor Aggregation
Medicine & Life Sciences
Cell Surface Receptors
Medicine & Life Sciences
IgE Receptors
Medicine & Life Sciences
Kinetics
Chemical Compounds
Proteins
Medicine & Life Sciences
Pancreatic Neoplasms
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1982 2018
Receptor Aggregation
Mast Cells
Ligands
Immunoglobulin E
Signal Transduction
NATIONAL FLOW CYTOMETRY AND SORTING RESEARCH RESOURCE
Posner, R. G., Waldren, C., Martin, D., Raju, M., Lehman, J., Bartholdi, M., Stallings, R., Stewart, C., Crawford, B., Crissman, H., Unkefer, P., Hoekstra, M., Leffert, H., Erickson, R., Priebe, W., Cobo, J., Shen, B., Waldo, G., Kunz, L., Smith, P., Sailer, B., Evenson, D., Narayanan, P., Yvonne, L., Burma, S., Vallarino, L., Smith, P., Burma, S., Phillips, A., Frangos, J., Smith, D., Capecchi, M., Vitharana, S., Ruscetti, T., Bradbury, A., Graves, S., Tsien, R., Waldo, G., Goodwin, P. M., Wilder, M., Hong, C., Jiang, Y., Espy, M. A., Mourant, J., Naivar, M., Gustafson, J., Juhong, L., Schaad, N., Pavlik, P., Serrano, E., Sanders, C., Kaduchak, G., Malloy, K., Gorenstein, D., Kuske, C., Sevick-Muraca, E., Chun, L., Applegate, R., Doorn, J., Goddard, G., Dichosa, A., Hong-Geller, E., Lillo, R., D'Anna, J. O. E., Steinkamp John, [. V., Lagarias, J. C., Kraakman-van der Zwet, M., Cornforth, M. N., Keller, R. A., Lopez, G. P., Novo, P. M., Goolsby, C. L., Hall, L., Th, J., Habbersett, R., D'Anna, J., Sklar, L. A., Freyer, J., Nolan, J., Zbigniew, D., Salzman, G., Hedley, D., Kraemer, P., Lehnert, B., Cram, S., Bradbury, E. M., Darzynkiewicz, Z., Martin, J., Steinkamp, J., Chen, D., Keng, P., Bell Prince, C., Marrone, B., Jett, J., Cram, S., Darzynkiewicz, Z., Chen, D., Habbersett, R., Cram, S., Sklar, L. A., Smith, P. & Steinkamp John
7/1/82 → 3/31/13
Project: Research project › Biotechnology Resource Grants
Receptor Aggregation
Immunoglobulin E
Ligands
Protein-Tyrosine Kinases
Signal Transduction
RECEPTOR AGGREGATION ON THE CELL SURFACE
9/1/93 → 2/28/08
Project: Research project › Research Project
Receptor Aggregation
Immunoglobulin E
Signal transduction
IgE Receptors
Agglomeration
Hardening Software for Rule-based Modeling.
Posner, R. G., Hlavacek, W. S. & Hlavacek, W. S.
8/1/14 → 4/30/18
Project: Research project › Research Project
Hardening
Phosphorylation
Simulators
Bifurcation (mathematics)
Distributed computer systems
Research Output 1985 2019
Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor
Erickson, K. E., Rukhlenko, O. S., Shahinuzzaman, M., Slavkova, K. P., Lin, Y. T., Suderman, R., Stites, E. C., Anghel, M., Posner, R. G., Barua, D., Kholodenko, B. N. & Hlavacek, W. S., Jan 1 2019, In : PLoS computational biology. 15, 1, p. e1006706Research output: Contribution to journal › Article
Somatomedin Receptors
Insulin
Growth Factors
Receptor
Phosphotyrosine
1
Citations
Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling
Rukhlenko, O. S., Khorsand, F., Krstic, A., Rozanc, J., Alexopoulos, L. G., Rauch, N., Erickson, K. E., Hlavacek, W. S., Posner, R. G., Gómez-Coca, S., Rosta, E., Fitzgibbon, C., Matallanas, D., Rauch, J., Kolch, W. & Kholodenko, B. N., Jan 1 2018, (Accepted/In press) In : Cell Systems.Research output: Contribution to journal › Article
MAP Kinase Signaling System
Drug Design
Mitogen-Activated Protein Kinase Kinases
Dimerization
Post Translational Protein Processing
New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling
Erickson, K. E., Rukhlenko, O. S., Posner, R. G., Hlavacek, W. S. & Kholodenko, B. N., Jan 1 2018, (Accepted/In press) In : Seminars in Cancer Biology.Research output: Contribution to journal › Article
Neoplasms
Protein Isoforms
Technology
Pharmaceutical Preparations
Genes
Using both qualitative and quantitative data in parameter identification for systems biology models
Mitra, E. D., Dias, R., Posner, R. G. & Hlavacek, W. S., Dec 1 2018, In : Nature Communications. 9, 1, 3901.Research output: Contribution to journal › Article
parameter identification
Systems Biology
biology
Identification (control systems)
Yeasts
A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients
Ramanathan, R. K., Weiss, G. J., Posner, R. G., Rajeshkumar, N. V., Jameson, G., Aziz, M., Hoering, A., Bolejack, V., Maitra, A., Fulk, M., Stites, E. C., Hlavacek, W. S., Gatalica, Z., Xiu, J., Hidalgo, M., Von Hoff, D. D. & Barrett, M. T., Dec 1 2017, In : Journal of Gastrointestinal Oncology. 8, 6, p. 925-935 11 p.Research output: Contribution to journal › Article
Pancreatic Neoplasms
Immunohistochemistry
Neoplasms
Biopsy
irinotecan